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MRC-5
Sign in to saveAlso known as MRC5, MRC 5, MRCV, MRC-V, Medical Research Council cell strain-5
thumb|MRC-5 cell MRC-5 (Medical Research Council cell strain 5) is a diploid cell culture line composed of fibroblasts, originally developed from the lung tissue of a 14-week-old aborted white male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings.
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thumb|MRC-5 cell MRC-5 (Medical Research Council cell strain 5) is a diploid cell culture line composed of fibroblasts, originally developed from the lung tissue of a 14-week-old aborted white male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings.
==Applications== MRC-5 cells are currently used to produce several vaccines including for hepatitis A, varicella and polio.