MTAP
Sign in to saveAlso known as BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus, methylthioadenosine phosphorylase
Gen der Spezies Homo sapiens
Gene data
MTAP- Name
- methylthioadenosine phosphorylase
- Type
- protein-coding
- Position
- 21,802,614–21,937,651 (+)
- Aliases
- BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus
- Ensembl
- ENSG00000099810
- RefSeq RNA
- NM_001396040.1, NM_001396041.1, NM_001396042.1, NM_001396043.1, NM_001396044.1
- RefSeq protein
- NP_001382969.1, NP_001382970.1, NP_001382971.1, NP_001382972.1, NP_001382973.1
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021].
Gene Ontology
Biological process
Molecular function
Pathways
Cysteine and methionine metabolism - Homo sapiens (human)Methionine salvage pathwayCytokine Signaling in Immune systemMetabolismSulfur amino acid metabolismImmune SystemInterleukin-12 family signalingSignaling by InterleukinsMetabolism of amino acids and derivativesGene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
via MyGene.info
Gene · Ensembl
methylthioadenosine phosphorylase
- Symbol
- MTAP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:21,802,614-21,937,651
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein MTAP PDB 1cb0.png
Show 8 more facts
- HomoloGene ID
- 1838
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4507
- genomic end
- 21931646
- genomic start
- 21802636
- chromosome
- human chromosome 9
- cytogenetic location
- 9p21.3
- expressed in
- gonad
Sources (4)
via Wikidata · CC0