SKIV2L2
Sign in to saveAlso known as Dob1, KIAA0052, Mtr4, fSAP118, Ski2 like RNA helicase 2, Mtr4 exosome RNA helicase
Gen der Spezies Homo sapiens
Gene data
MTREX- Name
- Mtr4 exosome RNA helicase
- Type
- protein-coding
- Position
- 55,307,736–55,426,075 (+)
- Aliases
- Dob1, KIAA0052, Mtr4, SKIV2L2, fSAP118
- Ensembl
- ENSG00000039123
- RefSeq RNA
- NM_015360.5
- RefSeq protein
- NP_056175.3
Enables ATP binding activity and RNA helicase activity. Involved in RNA catabolic process; cellular response to DNA damage stimulus; and maturation of 5.8S rRNA. Located in nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Colocalizes with nuclear exosome (RNase complex). Biomarker of amyotrophic lateral sclerosis. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
RNA degradation - Homo sapiens (human)Epigenetic regulation of gene expressionMajor pathway of rRNA processing in the nucleolus and cytosolmRNA Splicing - Major PathwaymRNA SplicingProcessing of Capped Intron-Containing Pre-mRNArRNA processingGene expression (Transcription)rRNA processing in the nucleus and cytosolMetabolism of RNA
via MyGene.info
Gene · Ensembl
Mtr4 exosome RNA helicase
- Symbol
- MTREX
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:55,307,736-55,426,075
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 6257
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23517
- genomic end
- 55425579
- genomic start
- 55307989
- chromosome
- human chromosome 5
- cytogenetic location
- 5q11.2
- expressed in
- islet of Langerhans
Sources (4)
via Wikidata · CC0