MTREX
Sign in to saveAlso known as Dob1, KIAA0052, Mtr4, fSAP118, Ski2 like RNA helicase 2, Mtr4 exosome RNA helicase, SKIV2L2
Superkiller viralicidic activity 2-like 2 is a protein that in humans is encoded by the SKIV2L2 gene.
In the Vinony graph
Within Vinony's link graph, MTREX is referenced by 1 other article, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Its subject is documented across 6 Wikipedia language editions.
Gene data
MTREX- Name
- Mtr4 exosome RNA helicase
- Type
- protein-coding
- Position
- 55,307,736–55,426,075 (+)
- Aliases
- Dob1, KIAA0052, Mtr4, SKIV2L2, fSAP118
- Ensembl
- ENSG00000039123
- RefSeq RNA
- NM_015360.5
- RefSeq protein
- NP_056175.3
Enables ATP binding activity and RNA helicase activity. Involved in RNA catabolic process; cellular response to DNA damage stimulus; and maturation of 5.8S rRNA. Located in nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Colocalizes with nuclear exosome (RNase complex). Biomarker of amyotrophic lateral sclerosis. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Mtr4 exosome RNA helicase
- Symbol
- MTREX
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:55,307,736-55,426,075
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 6257
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23517
- genomic end
- 55425579
- genomic start
- 55307989
- chromosome
- human chromosome 5
- cytogenetic location
- 5q11.2
- expressed in
- islet of Langerhans
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Superkiller viralicidic activity 2-like 2 is a protein that in humans is encoded by the SKIV2L2 gene.
==References==
Excerpted from Wikipedia’s “MTREX” article, available under the CC BY-SA 4.0 licence.