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EntityQ1137767· pop 44· linked from 624 articles

muscular dystrophy

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Also known as MD, Muscular dystrophy, MD

diseases that weaken the body's muscles

Key facts

Other names
Muscle dysfunction
Specialty
Neuromuscular medicine
Symptoms
Increasing weakening, breakdown of skeletal muscles , trouble walking
Duration
Chronic
Types
> 30, including Duchenne muscular dystrophy , Becker muscular dystrophy , facioscapulohumeral muscular dystrophy , limb–girdle muscular dystrophy , myotonic dystrophy
Causes
Genetic ( X-linked recessive , autosomal recessive , or autosomal dominant )
Diagnostic method
Genetic testing
Treatment
Pharmacotherapy , physical therapy , braces , corrective surgery , assisted ventilation
Prognosis
Depends on the particular disorder

via Wikipedia infobox

Research

45,415 papers

via PubMed

~9 min read

Encyclopedic overview

Muscular dystrophy (MD) is a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Some types are also associated with problems in other organs.

Over 30 different disorders are classified as muscular dystrophies. Of those, Duchenne muscular dystrophy (DMD) accounts for approximately 50% of cases and affects males beginning around the age of four. Other relatively common muscular dystrophies include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy, whereas limb–girdle muscular dystrophy and congenital muscular dystrophy are themselves groups of several – usually extremely rare – genetic disorders.

Excerpted from Wikipedia’s “muscular dystrophy” article, available under the CC BY-SA 4.0 licence.