myclobutanil

Also known as rac-myclobutanil

Myclobutanil is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor (CYP51) , specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes.

Research

347 papers

Myclobutanil-mediated alteration of liver-gut FXR signaling in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2023
Myclobutanil-induced testis damage and apoptotic germ cell death through ER stress and autophagy in mouse testes.Ecotoxicology and environmental safety · 2025
Myclobutanil induces neurotoxicity by activating autophagy and apoptosis in zebrafish larvae (Danio rerio).Chemosphere · 2024
Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
Myclobutanil induces cardiovascular toxicity via thyroid disruption in zebrafish larvae.Ecotoxicology and environmental safety · 2025

via PubMed

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Encyclopedic overview

5 sections

Contents

Stereoisomerism
Safety
Banned for cannabis cultivation
References
External links

== Stereoisomerism == {| class="wikitable" style="text-align:center;" |- class="hintergrundfarbe6" ! colspan="2" | Myclobutanil (2 stereoisomers) |- | 150px|(S)-Pefurazoat | 150px|(R)-Pefurazoat |} == Safety == The Safety Data Sheet indicates the following hazards: Suspected of damaging fertility or the unborn child. Toxic to aquatic life with long lasting effects. The first hazard has caused this chemical to be placed on the 1986 California Proposition 65 toxics list.

Excerpted from Wikipedia’s “myclobutanil” article, available under the CC BY-SA 4.0 licence.