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myclobutanil
Sign in to saveMyclobutanil is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor (CYP51) , specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes.
Research
347 papers- Myclobutanil-mediated alteration of liver-gut FXR signaling in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2023
- Myclobutanil-induced testis damage and apoptotic germ cell death through ER stress and autophagy in mouse testes.Ecotoxicology and environmental safety · 2025
- Myclobutanil induces neurotoxicity by activating autophagy and apoptosis in zebrafish larvae (Danio rerio).Chemosphere · 2024
- Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
- Myclobutanil induces cardiovascular toxicity via thyroid disruption in zebrafish larvae.Ecotoxicology and environmental safety · 2025
via PubMed
Article
5 sectionsContents
- Stereoisomerism
- Safety
- Banned for cannabis cultivation
- References
- External links
Myclobutanil is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor (CYP51) , specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes.
== Stereoisomerism == {| class="wikitable" style="text-align:center;" |- class="hintergrundfarbe6" ! colspan="2" | Myclobutanil (2 stereoisomers) |- | 150px|(S)-Pefurazoat | 150px|(R)-Pefurazoat |} == Safety == The Safety Data Sheet indicates the following hazards: Suspected of damaging fertility or the unborn child. Toxic to aquatic life with long lasting effects. The first hazard has caused this chemical to be placed on the 1986 California Proposition 65 toxics list.