MYO6

Name

myosin VI

Type

protein-coding

Position

75,748,788–75,919,537 (+)

Aliases

DFNA22, DFNB37

Ensembl

ENSG00000196586

RefSeq RNA

NM_001300899.2, NM_001368136.1, NM_001368137.1, NM_001368138.1, NM_001368139.1

RefSeq protein

NP_001287828.1, NP_001355065.1, NP_001355066.1, NP_001355067.1, NP_001355068.1

This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014].

via MyGene.info

Gene · Ensembl

myosin VI

Symbol

MYO6

Biotype

Protein coding

Organism

Homo sapiens

Location

6:75,748,788-75,919,537

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein MYO6 PDB 2bkh.png

via Wikidata · CC0