NEK8
Sign in to saveAlso known as JCK, NEK12A, NPHP9, RHPD2, NIMA related kinase 8
Serine/threonine-protein kinase Nek8, also known as never in mitosis A-related kinase 8, is an enzyme that in humans is encoded by the NEK8 gene.
Gene data
NEK8- Name
- NIMA related kinase 8
- Type
- protein-coding
- Position
- 28,725,897–28,743,455 (+)
- Aliases
- JCK, NEK12A, NPHP9, PKD8, RHPD2
- Ensembl
- ENSG00000160602
- RefSeq RNA
- NM_178170.3
- RefSeq protein
- NP_835464.1
This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
NIMA related kinase 8
- Symbol
- NEK8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:28,725,897-28,743,455
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Serine/threonine-protein kinase Nek8, also known as never in mitosis A-related kinase 8, is an enzyme that in humans is encoded by the NEK8 gene.
== Function ==
Excerpted from Wikipedia’s “NEK8” article, available under the CC BY-SA 4.0 licence.