NME8
Sign in to saveAlso known as CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2, HEL-S-99, NME/NM23 family member 8, DNAI8
Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.
Gene data
NME8- Name
- NME/NM23 family member 8
- Type
- protein-coding
- Aliases
- CILD6, DNAI8, HEL-S-99, NDK8, NM23-H8, SPTRX2, TXNDC3, sptrx-2
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9593
- exact match
- identifiers.org/ncbigene/51314
- genomic end
- 37900397
- genomic start
- 37888199
- cytogenetic location
- 7p14.1
Sources (3)
via Wikidata · CC0
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Article
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.
== Function ==