Structure via PubChem · Public domain (PubChem)
nolatrexed
Sign in to saveNolatrexed is a thymidylate synthase inhibitor.
Chemical data
- Formula
- C14H12N4OS
- Molecular weight
- 284.34 g/mol
- IUPAC name
- 2-amino-6-methyl-5-pyridin-4-ylsulfanyl-1H-quinazolin-4-one
- SMILES
- CC1=C(C2=C(C=C1)NC(=NC2=O)N)SC3=CC=NC=C3
- InChIKey
- XHWRWCSCBDLOLM-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 106 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- liver cancer
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 284.073
- Has use
- medication
Show 3 more facts
- canonical SMILES
- CC1=C(C2=C(C=C1)NC(=NC2=O)N)SC3=CC=NC=C3
- chemical formula
- C₁₄H₁₂N₄OS
- subject has role
- folic acid antagonists
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Nolatrexed is a thymidylate synthase inhibitor.
==References==
Excerpted from Wikipedia’s “nolatrexed” article, available under the CC BY-SA 4.0 licence.