NOP56
Sign in to saveAlso known as NOL5A, SCA36, NOP56 ribonucleoprotein
Nucleolar protein 56 is a protein that in humans is encoded by the NOP56 gene.
Gene data
NOP56- Name
- NOP56 ribonucleoprotein
- Type
- protein-coding
- Position
- 2,652,460–2,658,396 (+)
- Aliases
- NOL5A, SCA36
- Ensembl
- ENSG00000101361
- RefSeq RNA
- NM_006392.4, NR_027700.3, NR_145428.2
- RefSeq protein
- NP_006383.2
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NOP56 ribonucleoprotein
- Symbol
- NOP56
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:2,652,460-2,658,396
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4660
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10528
- genomic end
- 2639039
- genomic start
- 2652593
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Nucleolar protein 56 is a protein that in humans is encoded by the NOP56 gene.
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them have not been determined.
Excerpted from Wikipedia’s “NOP56” article, available under the CC BY-SA 4.0 licence.