nukleär lokaliseringsignal
Sign in to saveAlso known as nuclear localization signal, nuclear localization signals, nuclear localisation signal, nuclear localisation signals, nuclear localisation sequence, nuclear localisation sequences
type of amino acid sequence
Research
27,382 papers- cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.Biochemical and biophysical research communications · 1998
- Search for a nuclear localization signal in the prion protein.Molecular and cellular neurosciences · 1998
- The use of additive and subtractive approaches to examine the nuclear localization sequence of the polyomavirus major capsid protein VP1.Virology · 1992
- A missense mutation in the nuclear localization signal sequence of CERKL (p.R106S) causes autosomal recessive retinal degeneration.Molecular vision · 2008
- Characterization of cardiac muscle factor 1 sequence motifs: retinoblastoma protein binding and nuclear localization.Gene · 2002
via PubMed
Article · Svenska
Nukleär lokaliseringsignal eller NLS är en speciell aminosyrasekvens hos proteiner som signalerar för . En typ av transportproteiner kallade känner igen den specifika sekvensen och medierar sedan transporten genom kärnporerna in till cellkärnan. Olikt andra signalsekvenser klyvs inte NLS bort efter import till kärnan eftersom proteinerna ska kunna återföras till kärnan efter mitosen då kärnmembranet löses upp. Den första NLS som identifierades var Pro-Lys-Lys-Lys-Arg-Lys-Val.
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