File:Diagram_human_cell_nucleus_multilang.svg · Wikimedia Commons · See Wikimedia Commons
The nucleolus is a structure found inside the cell nucleus that plays a key role in making ribosomes, which are the cellular machines responsible for building proteins in living cells. This makes the nucleolus important for basic cell function, since producing proteins is essential for nearly all life processes.
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Research
18,968 papers- The nucleolus as a multiphase liquid condensate.ReviewNature reviews. Molecular cell biology · 2021Lafontaine DLJ, Riback JA, Bascetin R et al.DOI: 10.1038/s41580-020-0272-6
- The Nucleolus and Its Associated Pathologies.ReviewWIREs mechanisms of disease · 2025Menjivar-Vallecillo MJ, Padilla-Claros NV, Gavarrete-Garrido P et al.DOI: 10.1002/wsbm.70003
- The nucleolus of Giardia and its ribosomal biogenesis.ReviewParasitology research · 2023Lagunas-Rangel FADOI: 10.1007/s00436-023-07915-2
- The nucleolus.ReviewCold Spring Harbor perspectives in biology · 2011Pederson TDOI: 10.1101/cshperspect.a000638
- Nucleolus: A Central Hub for Nuclear Functions.ReviewTrends in cell biology · 2019Iarovaia OV, Minina EP, Sheval EV et al.DOI: 10.1016/j.tcb.2019.04.003
- The nucleolus.ReviewAnatomy and embryology · 1993Schwarzacher HG, Wachtler FDOI: 10.1007/BF00187008
- Therapeutic Approaches Targeting Nucleolus in Cancer.ReviewCells · 2019Carotenuto P, Pecoraro A, Palma G et al.DOI: 10.3390/cells8091090
- Mechanobiology of the Nucleolus.ReviewBiology of the cell · 2026Shetty Y, Dolega MEDOI: 10.1111/boc.70052
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Wikidata facts
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Article · Deutsch
Ein Nukleolus oder Nucleolus (von lateinisch nucleolus ‚Kernchen‘; Plural: nucleoli), auch Kernkörperchen genannt, ist ein lichtmikroskopisch auffälliger, etwa kugelförmiger Bereich des Nukleoplasmas innerhalb des Zellkerns (Nukleus) einer (eukaryotischen) Zelle. Nukleoli gehen aus bestimmten Chromosomenregionen hervor, den Nukleolusorganisatorregionen (NOR). Sie sind nach einer Kernteilung (Mitose) typischerweise in der Interphase zu finden und dienen dem Aufbau ribosomaler RNA. Im Nukleolus findet auch deren Zusammenbau mit ribosomalen Proteinen zu den Vorstufen von Ribosomen statt; sie ermöglichen die Proteinbiosynthese im Cytoplasma.
Abstract from DBpedia / Wikipedia · CC BY-SA
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