organoid
Sign in to savethumb|Intestinal organoid grown from Lgr5+ stem cells
Research
34,667 papers- Bioengineering Approaches for the Advanced Organoid Research.Advanced materials (Deerfield Beach, Fla.) · 2021
- Organoid cultures for cancer modeling.Cell stem cell · 2023
- Cancer research using organoid technology.Journal of molecular medicine (Berlin, Germany) · 2021
- Organoid Vascularization: Strategies and Applications.Advanced healthcare materials · 2025
- Organoid technology and applications in cancer research.Journal of hematology & oncology · 2018
via PubMed
Article
22 sectionsContents
- History
- Properties
- Process
- Types
- Cerebral organoid
- Gastrointestinal organoid
- Intestinal organoid
- Gastric organoid
- Liver and pancreatic organoids
- Lingual organoid
- Cerebellar organoid
- Cancer organoids
- Other
- Basic research
- Models of disease
- Personalized medicine
- Organoid transplants
- As a model for developmental biology
- See also
- References
- Further reading
- External links
thumb|Intestinal organoid grown from Lgr5+ stem cells
An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and biological complexity of that organ. It is derived from one or a few cells from a tissue, embryonic stem cells, or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities. The technique for growing organoids has rapidly improved since the early 2010s, and The Scientist named it one of the biggest scientific advancements of 2013. Scientists and engineers use organoids to study development and disease in the laboratory, for drug discovery and development in industry, personalized diagnostics and medicine, gene and cell therapies, tissue engineering, and regenerative medicine.