ORMDL3
Sign in to saveAlso known as ORMDL sphingolipid biosynthesis regulator 3
protein-coding gene in the species Homo sapiens
Gene data
ORMDL3- Name
- ORMDL sphingolipid biosynthesis regulator 3
- Type
- protein-coding
- Position
- 39,919,927–39,982,186 (−)
- Ensembl
- ENSG00000172057
- RefSeq RNA
- NM_001320801.2, NM_001320802.2, NM_001320803.1, NM_016471.2, NM_139280.4
- RefSeq protein
- NP_001307730.1, NP_001307731.1, NP_001307732.1, NP_644809.1, XP_047293049.1
Involved in ceramide metabolic process. Acts upstream of or within several processes, including negative regulation of B cell apoptotic process; negative regulation of ceramide biosynthetic process; and positive regulation of protein localization to nucleus. Located in endoplasmic reticulum. Part of SPOTS complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
negative regulation of B cell apoptotic processceramide metabolic processceramide metabolic processpositive regulation of autophagypositive regulation of autophagyintracellular sphingolipid homeostasisnegative regulation of ceramide biosynthetic processpositive regulation of protein localization to nucleus
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ORMDL sphingolipid biosynthesis regulator 3
- Symbol
- ORMDL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:39,919,927-39,982,186
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI