Orthoreovirus
Sign in to saveOrthoreovirus is a genus of viruses, in the family Reoviridae, in the subfamily Spinareovirinae. Vertebrates serve as natural hosts. There are ten species in this genus. Diseases associated with this genus include mild upper respiratory tract disease, gastroenteritis, and biliary atresia. Mammalian orthoreovirus 3 (strain dearing-T3D) induces cell death preferentially in transformed cells and therefore displays inherent oncolytic properties.
Species
GENUS
- KingdomViruses
- PhylumDuplornaviricota
- ClassResentoviricetes
- OrderReovirales
- FamilyReoviridae
via GBIF
Research
1,861 papers- Piscine orthoreovirus: Biology and distribution in farmed and wild fish.Journal of fish diseases · 2020
- Inactivation of Piscine orthoreovirus.Journal of fish diseases · 2020
- Pteropine orthoreovirus: An important emerging virus causing infectious disease in the tropics?Journal of infection in developing countries · 2017
- The Paradoxes of Viral mRNA Translation during Mammalian Orthoreovirus Infection.Viruses · 2021
- Orthoreovirus and Aquareovirus core proteins: conserved enzymatic surfaces, but not protein-protein interfaces.Virus research · 2004
via PubMed
~16 min read
Encyclopedic overview
14 sectionsContents
- History
- Classification
- Taxonomy
- Structure
- Strains
- Infection and transmission
- Replication
- Signs and symptoms
- Pathophysiology
- Oncolytic properties
- Diagnosis
- See also
- References
- External links
Orthoreovirus is a genus of viruses, in the family Reoviridae, in the subfamily Spinareovirinae. Vertebrates serve as natural hosts. There are ten species in this genus. Diseases associated with this genus include mild upper respiratory tract disease, gastroenteritis, and biliary atresia. Mammalian orthoreovirus 3 (strain dearing-T3D) induces cell death preferentially in transformed cells and therefore displays inherent oncolytic properties.
==History== The name "orthoreovirus" comes from the Greek word ortho, meaning "straight" and the reovirus, which comes from taking the letters: R, E, and O from "respiratory enteric orphan virus". The Orthoreovirus was named an orphan virus because it was not known to be associated with any known disease. It was discovered in the early 1950s when it was isolated from the respiratory as well as gastrointestinal tracts of both sick and healthy individuals
Excerpted from Wikipedia’s “Orthoreovirus” article, available under the CC BY-SA 4.0 licence.