Structure via PubChem · Public domain (PubChem)
oxandrolone
Sign in to saveAlso known as Anavar®, SC-11585, Oxandrolonum, Ossandrolone, Protivar, Oxandrolon, Oxandrolona
Oxandrolone is an androgen and synthetic anabolic steroid (AAS) medication to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications. It is taken by mouth. It was sold under the brand names Oxandrin and Anavar, among others.
In the Vinony graph
Vinony's link graph records 855 inbound references to oxandrolone, and connects out to United States Food and Drug Administration, anabolic steroid and biological half-life.
It sits within the topics Androgens, Androstanes and Appetite stimulants.
Vinony links it to 25 Wikipedia language editions.
Chemical data
- Formula
- C19H30O3
- Molecular weight
- 306.4 g/mol
- IUPAC name
- (1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(COC(=O)C4)C
- InChIKey
- QSLJIVKCVHQPLV-PEMPUTJUSA-N
- XLogP
- 3.7
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
662 papersvia PubMed
Wikidata facts
- Mass
- 306.219
Show 5 more facts
- chemical formula
- C₁₉H₃₀O₃
- isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(COC(=O)C4)C
- canonical SMILES
- CC12CCC3C(C1CCC2(C)O)CCC4C3(COC(=O)C4)C
- World Health Organisation international non-proprietary name
- oxandrolone
- Commons category
- Oxandrolone
via Wikidata · CC0
~19 min read
Encyclopedic overview
20 sectionsContents
- Medical uses
- Non-medical uses
- Contraindications
- Side effects
- Drug-drug interactions
- Pharmacology
- Pharmacodynamics
- Steroid configuration
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Availability
- United States
- Other countries
- Legal status
- References
- External links
Oxandrolone is an androgen and synthetic anabolic steroid (AAS) medication to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications. It is taken by mouth. It was sold under the brand names Oxandrin and Anavar, among others.
The drug is a synthetic androgen and anabolic steroid, hence is an agonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. Side effects of oxandrolone include severe cases of peliosis hepatis, sometimes associated with liver failure and intra-abdominal hemorrhage; liver tumors, sometimes fatal; and blood lipid changes associated with increased risk of atherosclerosis. Additional warnings include the risks associated with cholestatic hepatitis, hypercalcemia in patients with breast cancer, and increased risk for the development of prostatic hypertrophy and prostatic carcinoma in older patients. It has strong anabolic effects and weak androgenic effects, which gave it a mild side effect profile in that regard and made it especially suitable for use in women. Milder side effects in women were increased sexual desire, symptoms of hyperandrogenism such as acne, and symptoms of masculinization such as increased hair growth and voice changes.
Excerpted from Wikipedia’s “oxandrolone” article, available under the CC BY-SA 4.0 licence.