Research
404,976 papers- Oxidative stress: a concept in redox biology and medicine.Redox biology · 2015
- Oxidative stress and its role in cancer.Journal of cancer research and therapeutics · 2021
- Oxidative stress and antioxidant strategies in dermatology.Redox report : communications in free radical research · 2016
- Oxidative stress in Alzheimer's disease.Neuroscience bulletin · 2014
- The role of oxidative stress in intervertebral disc degeneration: Mechanisms and therapeutic implications.Ageing research reviews · 2024
via PubMed
~18 min read
Encyclopedic overview
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA.
Excerpted from Wikipedia’s “oxidative stress” article, available under the CC BY-SA 4.0 licence.