hepatotoxicity
Sign in to saveAlso known as liver damage, toxic hepatitis, chemical or drug-induced liver injury, Chemical and Drug Induced Liver Injury
{| class="infobox" style="font-size: 88%; text-align: center; width: 22em; line-height: 1.5em" ! Synonyms |- | Drug-induced liver injury (DILI) Toxin-induced hepatitis Drug-induced hepatitis Drug-induced hepatic necrosis Drug-induced hepatic fibrosis Drug-induced hepatic granuloma Toxic liver disease with hepatitis Toxic liver disease with cholestasisToxic hepatitis Toxic liver diseaseToxin-induced liver diseaseDrug-induced liver diseaseDrug-induced liver damageHepatogenous poisoning |}
In the Vinony graph
Within Vinony's link graph, hepatotoxicity is referenced by 505 other articles, and connects out to Paracetamol, redox and parenchyma.
It sits within the topics Diseases of liver, Hepatology and Toxicology.
Its subject is documented across 22 Wikipedia language editions.
Key facts
- Medical condition (new).synonyms
- see below list
- Medical condition (new).image
- Drug-induced hepatitis low mag.jpg
- Medical condition (new).caption
- Drug-induced hepatitis with granulomata. Other causes were excluded with extensive investigations. Liver biopsy. H&E stain.
- Medical condition (new).field
- Gastroenterology, Toxicology
- Medical condition (new).complications
- Cirrhosis, liver failure
via Wikipedia infobox
Research
35,393 papers- Hepatotoxicity induced by nanomaterials: mechanisms and in vitro models.Archives of toxicology · 2021
- Hepatotoxicity due to dietary supplements: state-of-the-art, gaps and perspectives.Critical reviews in toxicology · 2023
- Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug.Drug metabolism and disposition: the biological fate of chemicals · 2021
- Possible Pathways of Hepatotoxicity Caused by Chemical Agents.Current drug metabolism · 2019
- [Once upon a time the hepatotoxicity…].Medecine sciences : M/S · 2021
via PubMed
Wikidata facts
- Subclass of
- toxicity
Show 2 more facts
- health specialty
- gastroenterology
- NCI Thesaurus ID
- C84427
Sources (2)
via Wikidata · CC0
~20 min read
Encyclopedic overview
26 sectionsContents
- Causes
- Paracetamol
- Nonsteroidal anti-inflammatory drugs
- Glucocorticoids
- Isoniazid
- Other hydrazine derivative drugs
- Natural products
- Alternative remedies
- Industrial toxin
- Mechanism
- Drug metabolism in liver
- Patterns of injury
- Zonal necrosis
- Hepatitis
- Cholestasis
- Steatosis
- Granuloma
- Vascular lesions
- Neoplasm
- Diagnosis
- Treatment
- Prognosis
- Drugs withdrawn
- See also
- References
- External links
{| class="infobox" style="font-size: 88%; text-align: center; width: 22em; line-height: 1.5em" ! Synonyms |- | Drug-induced liver injury (DILI) Toxin-induced hepatitis Drug-induced hepatitis Drug-induced hepatic necrosis Drug-induced hepatic fibrosis Drug-induced hepatic granuloma Toxic liver disease with hepatitis Toxic liver disease with cholestasisToxic hepatitis Toxic liver diseaseToxin-induced liver diseaseDrug-induced liver diseaseDrug-induced liver damageHepatogenous poisoning |}
Hepatotoxicity refers to chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Excerpted from Wikipedia’s “hepatotoxicity” article, available under the CC BY-SA 4.0 licence.