OXR1
Sign in to saveAlso known as TLDC3, Nbla00307, oxidation resistance 1, CHEGDD
Oxidation resistance protein 1 is a protein that in humans is encoded by the OXR1 gene. Loss of OXR1 function causes decline of the retromer complex.
Gene data
OXR1- Name
- oxidation resistance 1
- Type
- protein-coding
- Position
- 106,270,112–106,752,711 (+)
- Aliases
- CHEGDD, Nbla00307, TLDC3
- Ensembl
- ENSG00000164830
- RefSeq RNA
- NM_001198532.1, NM_001198533.2, NM_001198534.1, NM_001198535.1, NM_018002.3
- RefSeq protein
- NP_001185461.1, NP_001185462.1, NP_001185463.1, NP_001185464.1, NP_060472.2
Predicted to enable oxidoreductase activity. Predicted to be involved in response to oxidative stress. Predicted to act upstream of or within several processes, including adult walking behavior; negative regulation of neuron death; and negative regulation of peptidyl-cysteine S-nitrosylation. Predicted to be located in mitochondrion and nucleolus. Predicted to be active in nucleus. Implicated in cerebellar hyplasia/atrophy, epilepsy, and global developmental delay. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
oxidation resistance 1
- Symbol
- OXR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:106,270,112-106,752,711
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 24993
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55074
- genomic end
- 107764922
- genomic start
- 106270144
- chromosome
- human chromosome 8
- cytogenetic location
- 8q23.1
- expressed in
- prefrontal cortex
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Oxidation resistance protein 1 is a protein that in humans is encoded by the OXR1 gene. Loss of OXR1 function causes decline of the retromer complex.
==References==
Excerpted from Wikipedia’s “OXR1” article, available under the CC BY-SA 4.0 licence.