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Pirenoxine

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Pirenoxine

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Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts.

Chemical data

Formula
C16H8N2O5
Molecular weight
308.24 g/mol
IUPAC name
1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
SMILES
C1=CC=C2C(=C1)N=C3C(=CC(=O)C4=C3C(=O)C=C(N4)C(=O)O)O2
InChIKey
OKPNYGAWTYOBFZ-UHFFFAOYSA-N
XLogP
1.3
Polar surface area
105 Ų
H-bond donors
2
H-bond acceptors
7
Formal charge
0

via PubChem

Wikidata facts

Subclass of
carboxylic acid
Mass
308.0433213559999
Show 3 more facts
chemical formula
C₁₆H₈N₂O₅
canonical SMILES
c1ccc2c(c1)nc-3c4c(cc(nc4c(=O)cc3o2)C(=O)O)O
NCI Thesaurus ID
C66416
Sources (2)

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Encyclopedic overview

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Contents
  • References

Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts.

A report in the Inorganic Chemistry journal showed that in liquid solutions, pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye. Pirenoxine interacts with selenite or calcium ions that have been proven as factors leading to the formation of lens cataract.

Excerpted from Wikipedia’s “Pirenoxine” article, available under the CC BY-SA 4.0 licence.

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