poliovirus
Sign in to savePoliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae. There are three poliovirus serotypes, numbered 1, 2, and 3.
Research
19,560 papers- Wild and vaccine-derived poliovirus circulation, and implications for polio eradication.Epidemiology and infection · 2017
- Vaccine-derived polioviruses.The Journal of infectious diseases · 2014
- Schizophrenia, catatonic schizophrenia and poliovirus - a role for natural experiments?Acta psychiatrica Scandinavica · 2021
- Evolution and polymorphism of poliovirus genomes.Biologicals : journal of the International Association of Biological Standardization · 1993
- Poliovirus vaccine and vaccine-derived polioviruses.The New England journal of medicine · 2010
via PubMed
Article
16 sectionsContents
- Replication cycle
- Origin and serotypes
- Pathogenesis
- Immune system avoidance
- Eradication
- Research
- Transgenic mice
- Genetic modification
- History
- Discovery
- Genome
- Structure
- Cloning
- Synthesis
- References
- External links
Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae. There are three poliovirus serotypes, numbered 1, 2, and 3.
Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only a strand of RNA and a nonenveloped icosahedral protein coat encapsulating it—poliovirus is widely regarded as the simplest significant virus.