poloxamer
Sign in to savethumb|General structurewith a = 2–130 and b = 15–67
Article
10 sectionsContents
- Common poloxamer properties
- Micellization and phase transitions
- Uses
- Biological effect
- On multi drug resistant cancer cells
- On nuclear factor kappa B
- Potential degradation by sonication
- References
- Further reading
- External links
thumb|General structurewith a = 2–130 and b = 15–67
Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide)). The word was coined by BASF inventor, Irving Schmolka, who received the patent for these materials in 1973. Poloxamers are also known by the trade names Pluronic, Kolliphor (pharma grade), and Synperonic.