polisoma
Also known as GO:0005844, polyribosome, ergosome
thumb|Several ribosomes synthesizing a polypeptide on the same mRNA strand A polysome (or polyribosome or ergosome) is a group of ribosomes bound to an mRNA molecule like "beads" on a "thread". It consists of a complex of an mRNA molecule and two or more ribosomes that act to translate mRNA instructions into polypeptides. Originally coined "ergosomes" in 1963, they were further characterized by Jonathan Warner, Paul M. Knopf, and Alex Rich.
Research
13,200 papers- Analysis of translation using polysome profiling.Nucleic acids research · 2017
- m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.Molecular cell · 2023
- Polysome sorting controls mRNA localization and protein fate.Trends in cell biology · 2026
- Single polysome analysis of mRNP.Biochemical and biophysical research communications · 2022
- Polysome profile analysis--yeast.Methods in enzymology · 2013
via PubMed
Article · Italiano
I polisomi (o poliribosomi) sono ribosomi associati allo stesso mRNA che attuano una codifica di proteine in serie. Nei polisomi, più ribosomi si legano alla stessa molecola di RNA messaggero attraverso la quale si muovono dal codone iniziale fino a quello finale, in direzione 3'. I polisomi rendono possibile la rapida sintesi di copie multiple di un polipeptide a partire dalle istruzioni trasportate da un'unica molecola di mRNA.
Abstract from DBpedia / Wikipedia · CC BY-SA