POU2F3

Name

POU class 2 homeobox 3

Type

protein-coding

Position

120,236,640–120,319,945 (+)

Aliases

Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a

Ensembl

ENSG00000137709

RefSeq RNA

NM_001244682.2, NM_014352.4, XM_011542739.3, XM_011542740.3, XM_011542741.4

RefSeq protein

NP_001231611.1, NP_055167.2, XP_011541041.1, XP_011541042.1, XP_011541043.1

This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

via MyGene.info

Gene · Ensembl

POU class 2 homeobox 3

Symbol

POU2F3

Biotype

Protein coding

Organism

Homo sapiens

Location

11:120,236,640-120,320,040

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein POU2F3 PDB 1pou.png

via Wikidata · CC0