PPP1R9B

Also known as PPP1R6, PPP1R9, SPINO, Spn, protein phosphatase 1 regulatory subunit 9B

Neurabin-2 is a protein that in humans is encoded by the PPP1R9B gene.

Gene data

PPP1R9B

Name: protein phosphatase 1 regulatory subunit 9B
Type: protein-coding
Position: 50,133,732–50,151,020 (−)
Aliases: PPP1R6, PPP1R9, SPINO, Spn
Ensembl: ENSG00000108819
RefSeq RNA: NM_032595.5
RefSeq protein: NP_115984.3

This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors. [provided by RefSeq, Feb 2014].

via MyGene.info

Gene · Ensembl

protein phosphatase 1 regulatory subunit 9B

Symbol: PPP1R9B
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:50,133,732-50,151,020
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

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Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

Neurabin-2 is a protein that in humans is encoded by the PPP1R9B gene.

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997).[supplied by OMIM]

Excerpted from Wikipedia’s “PPP1R9B” article, available under the CC BY-SA 4.0 licence.