PRDM2

Name

PR/SET domain 2

Type

protein-coding

Aliases

HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

via MyGene.info

Gene · Ensembl

PR/SET domain 2

Symbol

PRDM2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:13,699,989-13,825,093

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein PRDM2 PDB 2JV0.png

via Wikidata · CC0