PRIM1
Sign in to saveAlso known as p49, primase (DNA) subunit 1, DNA primase subunit 1
DNA primase small subunit is in humans is encoded by the PRIM1 gene and is part of the enzyme DNA polymerase alpha.
Gene data
PRIM1- Name
- DNA primase subunit 1
- Type
- protein-coding
- Position
- 56,730,438–56,752,384 (−)
- Aliases
- PDIL, p49
- Ensembl
- ENSG00000198056
- RefSeq RNA
- NM_000946.3
- RefSeq protein
- NP_000937.1
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DNA primase subunit 1
- Symbol
- PRIM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:56,730,438-56,752,384
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
DNA primase small subunit is in humans is encoded by the PRIM1 gene and is part of the enzyme DNA polymerase alpha.
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
Excerpted from Wikipedia’s “PRIM1” article, available under the CC BY-SA 4.0 licence.
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