propargyl amine
Sign in to saveAlso known as prop-2-yn-1-amine, 2-Propynylamine, 2-Propyn-1-amine, Prop-2-ynylamine, mono-Propargylamine, propargylamine
Propargylamine is an organic compound with the formula HC≡CCH2NH2. It is a colorless, odorless liquid that is used as a precursor to other compounds. Propargyl amines are produced by reactions of amines with propargyl halides.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 55.042
Show 3 more facts
- chemical formula
- C₃H₅N
- canonical SMILES
- C#CCN
- Commons category
- Propargyl amine
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Encyclopedic overview
2 sectionsContents
- Drugs
- References
Propargylamine is an organic compound with the formula HC≡CCH2NH2. It is a colorless, odorless liquid that is used as a precursor to other compounds. Propargyl amines are produced by reactions of amines with propargyl halides.
The behavior of propargyl amine is illustrated by its acylation benzoyl chloride to the amide. A Sonogashira coupling of the terminal alkyne end with another equivalent of benzoylchloride gives the dicarbonyl, a precursor to an oxazole. 300px|oxazoline from propargyl amides Merkul 2006 ==Drugs== Propargylamine is used in the synthesis of: Etintidine [69539-53-3] 2-PAT HDAC1/MAO-B-IN-1 [2759855-37-1]
Excerpted from Wikipedia’s “propargyl amine” article, available under the CC BY-SA 4.0 licence.