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EntityQ7253051· pop 8· linked from 636 articles

Also known as 4',5-dihydroxy-7-methoxyisoflavone, 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxychromen-4-one, 4',5-dihydroxy-7-methoxygenistein, 7-O-methyl-genistein, 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4-benzopyrone, 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one, 5,4'-dihydroxy-7-methoxyisoflavone, padmakastein

Prunetin is an O-methylated isoflavone, a type of flavonoid. It has been isolated for the first time by Finnemore in 1910 in the bark of Prunus emarginata (the Oregon cherry). Prunetin isolated from pea roots can act as an attractant for Aphanomyces euteiches zoospores. It is also an allosteric inhibitor of human liver aldehyde dehydrogenase.

Wikidata facts

Subclass of
isoflavone
Mass
284.068473
Show 5 more facts
chemical formula
C₁₆H₁₂O₅
canonical SMILES
COC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC=C(C=C3)O)O
has characteristic
bitterness
Commons category
Prunetin
Sources (2)

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Encyclopedic overview

3 sections
Contents
  • Glycosides
  • See also
  • References

Prunetin is an O-methylated isoflavone, a type of flavonoid. It has been isolated for the first time by Finnemore in 1910 in the bark of Prunus emarginata (the Oregon cherry). Prunetin isolated from pea roots can act as an attractant for Aphanomyces euteiches zoospores. It is also an allosteric inhibitor of human liver aldehyde dehydrogenase.

Prunetin can lower blood pressure of spontaneously hypertensive rats and relax isolated rat aortic rings through calcium channel block mechanisms in vessel smooth muscles.

Excerpted from Wikipedia’s “prunetin” article, available under the CC BY-SA 4.0 licence.

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