PTTG1IP
Sign in to saveAlso known as C21orf1, C21orf3, PBF, pituitary tumor-transforming 1 interacting protein, PTTG1 interacting protein, PTTG1IP1
Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1), also known as PTTG1-binding factor (PBF), is a poorly characterised protein that in humans is encoded by the PTTG1IP gene located within the chromosomal region 21q22.3.
Gene data
PTTG1IP- Name
- PTTG1 interacting protein
- Type
- protein-coding
- Position
- 44,849,585–44,873,903 (−)
- Aliases
- C21orf1, C21orf3, PBF, PTTG1IP1
- Ensembl
- ENSG00000183255
- RefSeq RNA
- NM_001286822.2, NM_004339.4, NR_104597.2
- RefSeq protein
- NP_001273751.1, NP_004330.1
This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
PTTG1 interacting protein
- Symbol
- PTTG1IP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:44,849,585-44,873,903
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3203
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/754
- chromosome
- human chromosome 21
- genomic start
- 46269500
- genomic end
- 46293752
- cytogenetic location
- 21q22.3
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Structure
- Function
- Interactions
- References
- Further reading
Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1), also known as PTTG1-binding factor (PBF), is a poorly characterised protein that in humans is encoded by the PTTG1IP gene located within the chromosomal region 21q22.3.
== Structure ==
Excerpted from Wikipedia’s “PTTG1IP” article, available under the CC BY-SA 4.0 licence.