Structure via PubChem · Public domain (PubChem)
pyrazolanthrone
Sign in to saveAlso known as 1,9-pyrazoloanthrone, JNK Inhibitor II, SP 600125, C.I. 70300, Pyrazoleanthrone, 2H-dibenzo[cd,g]indazol-6-one, 2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One
1,9-Pyrazoloanthrone is a chemical compound that is a derivative of anthrone. It is used in biochemical studies as an inhibitor of c-Jun N-terminal kinases (JNKs).
Chemical data
- Formula
- C14H8N2O
- Molecular weight
- 220.23 g/mol
- IUPAC name
- 14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one
- SMILES
- C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
- InChIKey
- ACPOUJIDANTYHO-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 45.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 220.064
Show 2 more facts
- chemical formula
- C₁₄H₈N₂O
- canonical SMILES
- C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
1,9-Pyrazoloanthrone is a chemical compound that is a derivative of anthrone. It is used in biochemical studies as an inhibitor of c-Jun N-terminal kinases (JNKs).
Derivatives of 1,9-pyrazoloanthrone have a variety of biological activities. For example, 5-(aminoalkyl)amino derivatives have been investigated as anticancer agents.
Excerpted from Wikipedia’s “pyrazolanthrone” article, available under the CC BY-SA 4.0 licence.