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GeneQ18030993· pop 6· linked from 24 articles

RAB5A

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Also known as RAB5, RAB5A, member RAS oncogene family

Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.

Gene data

RAB5A

Name: RAB5A, member RAS oncogene family
Type: protein-coding
Position: 19,947,097–19,985,178 (+)
Aliases: RAB5
Ensembl: ENSG00000144566
RefSeq RNA: NM_001292048.2, NM_004162.5, XM_047448648.1, XM_054347413.1
RefSeq protein: NP_001278977.1, NP_004153.2, XP_047304604.1, XP_054203388.1

Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including amyloid-beta clearance by transcytosis; early endosome to late endosome transport; and regulation of exocytosis. Located in several cellular components, including cytoplasmic side of early endosome membrane; nucleoplasm; and terminal bouton. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

intracellular protein transport endocytosis endocytosis endocytosis endosomal transport endosomal transport endosomal transport endosomal transport

Molecular function

GTPase activity GTPase activity GTPase activity GTPase activity G protein activity G protein activity G protein activity G protein activity

Cellular component

ruffle cytoplasm cytoplasm endosome endosome early endosome early endosome early endosome

Pathways

Ras signaling pathway - Homo sapiens (human)Endocytosis - Homo sapiens (human)Phagosome - Homo sapiens (human)Vasopressin-regulated water reabsorption - Homo sapiens (human)Amyotrophic lateral sclerosis - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)Salmonella infection - Homo sapiens (human)Amoebiasis - Homo sapiens (human)Tuberculosis - Homo sapiens (human)Hemostasis

via MyGene.info

Wikidata facts

Image: Protein RAB5A PDB 1huq.png

Show 5 more facts

HomoloGene ID: 68142
exact match: identifiers.org/ncbigene/5868
genomic end: 20026667
genomic start: 19947097
cytogenetic location: 3p24.3

Sources (4)

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Article

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Contents

Function
Interactions
References
Further reading

Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.

== Function ==

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Categories

Genes on human chromosome 3