SDCBP

Name

syndecan binding protein

Type

protein-coding

Position

58,552,924–58,583,800 (+)

Aliases

MDA-9, MDA9, SDCBP1, ST1, SYCL, TACIP18

Ensembl

ENSG00000137575

RefSeq RNA

NM_001007067.2, NM_001007068.2, NM_001007069.2, NM_001007070.2, NM_001330537.2

RefSeq protein

NP_001007068.1, NP_001007069.1, NP_001007070.1, NP_001007071.1, NP_001317466.1

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017].

via MyGene.info

Wikidata facts

Image

Protein SDCBP PDB 1n99.png

via Wikidata · CC0