RAD9A

Name

RAD9 checkpoint clamp component A

Type

protein-coding

Position

67,317,871–67,398,412 (+)

Aliases

RAD9

Ensembl

ENSG00000172613

RefSeq RNA

NM_001243224.1, NM_004584.3, XM_006718652.4, XM_017018098.2, XM_047427381.1

RefSeq protein

NP_001230153.1, NP_004575.1, XP_006718715.1, XP_016873587.1, XP_047283337.1

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

via MyGene.info

Gene · Ensembl

RAD9 checkpoint clamp component A

Symbol

RAD9A

Biotype

Protein coding

Organism

Homo sapiens

Location

11:67,317,871-67,398,412

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein RAD9A PDB 3A1J.png

via Wikidata · CC0