RASGRP2

Name

RAS guanyl releasing protein 2

Type

protein-coding

Position

64,726,905–64,745,456 (−)

Aliases

CALDAG-GEFI, CDC25L

Ensembl

ENSG00000068831

RefSeq RNA

NM_001098670.2, NM_001098671.2, NM_001318398.2, NM_001440690.1, NM_001440691.1

RefSeq protein

NP_001092140.1, NP_001092141.1, NP_001305327.1, NP_001427619.1, NP_001427620.1

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].

via MyGene.info

Gene · Ensembl

RAS guanyl releasing protein 2

Symbol

RASGRP2

Biotype

Protein coding

Organism

Homo sapiens

Location

11:64,726,905-64,745,456

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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