RCHY1
Sign in to saveAlso known as ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363, ring finger and CHY zinc finger domain containing 1
RING finger and CHY zinc finger domain-containing protein 1 is a protein that in humans is encoded by the RCHY1 gene.
Gene data
RCHY1- Name
- ring finger and CHY zinc finger domain containing 1
- Type
- protein-coding
- Position
- 75,479,033–75,514,764 (−)
- Aliases
- ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
- Ensembl
- ENSG00000163743
- RefSeq RNA
- NM_001008925.2, NM_001009922.3, NM_001278536.2, NM_001278537.2, NM_001278538.2
- RefSeq protein
- NP_001009922.1, NP_001265465.1, NP_001265466.1, NP_001265467.1, NP_001265468.1
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein RCHY1 PDB 2JRJ.png
Show 3 more facts
- HomoloGene ID
- 22894
- exact match
- identifiers.org/ncbigene/25898
- cytogenetic location
- 4q21.1
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Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
RING finger and CHY zinc finger domain-containing protein 1 is a protein that in humans is encoded by the RCHY1 gene.
== Function ==