REG1B

Also known as PSPS2, REGH, REGI-BETA, REGL, regenerating family member 1 beta

Lithostathine-1-beta is a protein that in humans is encoded by the REG1B gene.

Gene data

REG1B

Name: regenerating family member 1 beta
Type: protein-coding
Position: 79,085,023–79,088,019 (−)
Aliases: PSPS2, REGH, REGI-BETA, REGL
Ensembl: ENSG00000172023
RefSeq RNA: NM_006507.4
RefSeq protein: NP_006498.1

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008].