retinoblastoma
Sign in to saveAlso known as RB, RB - Retinoblastoma, neuroblastoma of Retina, retinal neuroblastoma, Retinal Neuroblastoma, Neuroblastoma of Retina, retina neuroblastoma, Neuroblastoma of the Retina
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye. It is the most common primary malignant intraocular cancer in children, and 80% of retinoblastoma cases are first detected in those under 3 years old.
Key facts
- Medical condition (new).name
- Retinoblastoma
- Medical condition (new).image
- Retinoblastoma_in_enucleated_eyeball.jpg
- Medical condition (new).caption
- A pathology specimen of a retinoblastoma tumor from an enucleated eye of a 3-year-old female
- Medical condition (new).field
- Neuro-oncology
- Medical condition (new).symptoms
- Leukocoria seen in patient's pupil in photosPoor visionOne or both eyes turning inward or outwardEye pain
- Medical condition (new).onset
- Under 3 years old
- Medical condition (new).treatment
- Surgery (including eye removal in advanced cases)Chemotherapy (after surgery in cases of metastasis)Focal therapy
- Medical condition (new).frequency
- ~250–300 children diagnosed annually (United States)
via Wikipedia infobox
Research
26,240 papers- Retinoblastoma - A comprehensive review, update and recent advances.Indian journal of ophthalmology · 2024
- Mutation and cancer: statistical study of retinoblastoma.Proceedings of the National Academy of Sciences of the United States of America · 1971
- Retinoblastoma.Orphanet journal of rare diseases · 2006
- [Retinoblastoma].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
- Trilateral retinoblastoma: A systematic review of 211 cases.Neurosurgical review · 2019
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- Retinoblastoma.jpg
Show 9 more facts
- NCI Thesaurus ID
- C6956
- Commons category
- Retinoblastoma
- health specialty
- oncology
- exact match
- identifiers.org/doid/DOID:768
- drug or therapy used for treatment
- (RS)-cyclophosphamide
- genetic association
- MYCN
- on focus list of Wikimedia project
- WikiProject Medicine
- has cause
- gene duplication
- symptoms and signs
- neovascular glaucoma
Sources (8)
via Wikidata · CC0
~22 min read
Encyclopedic overview
18 sectionsContents
- Epidemiology
- Signs and symptoms
- Cause
- RB1
- MYCN
- Diagnosis
- Classification
- Differential diagnosis
- Morphology
- Genetic testing
- Imaging
- Staging
- Treatment
- Prognosis
- Culture
- See also
- References
- External links
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye. It is the most common primary malignant intraocular cancer in children, and 80% of retinoblastoma cases are first detected in those under 3 years old.
Though most children in high income countries survive this cancer, they may lose their vision in the affected eye(s) or need to have the eye removed.
Excerpted from Wikipedia’s “retinoblastoma” article, available under the CC BY-SA 4.0 licence.