MYCN

Also known as MODED, N-myc, NMYC, ODED, bHLHe37, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, MYCN proto-oncogene, bHLH transcription factor, MYCNsORF

N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene.

Gene data

MYCN

Name: MYCN proto-oncogene, bHLH transcription factor
Type: protein-coding
Aliases: FGLDS1, MODED, MPAPA, MYCNsORF, MYCNsPEP, N-myc, NMYC, ODED, bHLHe37

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014].

via MyGene.info

Gene · Ensembl

MYCN proto-oncogene, bHLH transcription factor

Symbol: MYCN
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:15,938,396-15,947,022
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: MYCN structure.png

Show 5 more facts

HomoloGene ID: 3922
exact match: identifiers.org/ncbigene/4613
genomic end: 16087129
genomic start: 15940550
cytogenetic location: 2p24.3

Sources (6)

via Wikidata · CC0

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Article

7 sections

Contents

Function
Clinical significance
Interactions
See also
References
Further reading
External links

N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene.

== Function ==