rutin

Also known as 3-Rhamnoglucosylquercetin, 3-Rutinosyl quercetin, 3,3',4',5,7-Pentahydroxyflavone-3-rutinoside, Rutinoside, quercetin 3beta-, Glucopyranoside, quercetin-3 6-O-alpha-L-rhamnopyranosyl-,beta-D, Quercetin 3-O-beta-D-rutinoside, Eldrin, Tanrutin

Rutin (rutoside, quercetin-3-O-rutinoside or sophorin) is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid glycoside found in a wide variety of plants, including citrus.

Chemical data

Formula: C27H30O16
Molecular weight: 610.5 g/mol
IUPAC name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
InChIKey: IKGXIBQEEMLURG-NVPNHPEKSA-N
XLogP: -1.3
Polar surface area: 266 Å²
H-bond donors: 10
H-bond acceptors: 16
Formal charge: 0

via PubChem

Research

11,591 papers

Rutin attenuates inflammation by downregulating AGE-RAGE signaling pathway in psoriasis: Network pharmacology analysis and experimental evidence.International immunopharmacology · 2023
Therapeutic benefits of rutin and its nanoformulations.Phytotherapy research : PTR · 2021
Nano-Rutin: A Promising Solution for Alleviating Various Disorders.Recent patents on nanotechnology · 2025
Tartary buckwheat rutin: Accumulation, metabolic pathways, regulation mechanisms, and biofortification strategies.Plant physiology and biochemistry : PPB · 2024
Rutin-Associated Hepatoprotection: A Review of Mechanisms and Therapeutic Prospects.Basic & clinical pharmacology & toxicology · 2025

via PubMed

Wikidata facts

Mass: 610.153
Image: Rutin by Danny S. - 001.JPG

Show 5 more facts

chemical formula: C₂₇H₃₀O₁₆
Commons category: Rutin
isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
canonical SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
World Health Organisation international non-proprietary name: rutoside

Sources (5)

via Wikidata · CC0

~4 min read

Article

7 sections

Contents

Occurrences
Metabolism
In food
Research
Biosynthesis
References
External links

== Occurrences == Rutin is one of the phenolic compounds found in the plant species Carpobrotus edulis. Its name comes from the name of Ruta graveolens, a plant that also contains rutin. Various citrus fruit peels contain 32 to 49 mg per g of flavonoids expressed as rutin equivalents. Citrus leaves contain rutin at concentrations of 11 mg per g in orange trees and 7 mg per g in lime trees. In 2021, Samoan researchers identified rutin in the native plant matalafi (Psychotria insularum).