S100A2
Sign in to saveAlso known as CAN19, S100L, S100 calcium binding protein A2
S100 calcium-binding protein A2 (S100A2) is a protein that in humans is encoded by the S100A2 gene and it is located on chromosome 1q21 with other S100 proteins.
Gene data
S100A2- Name
- S100 calcium binding protein A2
- Type
- protein-coding
- Position
- 153,560,950–153,586,676 (−)
- Aliases
- CAN19, S100L
- Ensembl
- ENSG00000196754
- RefSeq RNA
- NM_001366406.1, NM_001366407.1, NM_005978.4, XM_047427373.1, XM_054338109.1
- RefSeq protein
- NP_001353335.1, NP_001353336.1, NP_005969.2, XP_047283329.1, XP_054194084.1
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Wikidata facts
- Instance of
- gene
- Image
- Protein S100A2 PDB 2RGI.png
Show 5 more facts
- HomoloGene ID
- 48389
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6273
- cytogenetic location
- 1q21.3
- expressed in
- nipple
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Tissue and subcellular distribution
- Function
- Clinical significance
- References
- Further reading
S100 calcium-binding protein A2 (S100A2) is a protein that in humans is encoded by the S100A2 gene and it is located on chromosome 1q21 with other S100 proteins.
== Tissue and subcellular distribution ==
Excerpted from Wikipedia’s “S100A2” article, available under the CC BY-SA 4.0 licence.