SAR1B

Also known as ANDD, CMRD, GTBPB, SARA2, secretion associated Ras related GTPase 1B

REDIRECT COPII

Gene data

SAR1B

Name: secretion associated Ras related GTPase 1B
Type: protein-coding
Aliases: ANDD, CMRD, GTBPB, SARA2

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010].

via MyGene.info