COPII
Sign in to savethumb|dark green: Protein transport protein Sec23A, Homo sapiens, Gene names: SEC23Abrown: Protein transport protein Sec24A, Homo sapiens, Gene names: [[SEC24Ablue: Vesicle-trafficking protein SEC22b, Mus musculus, Gene names: SEC22B, Sec22l1pink: C-terminal sorting motif ILE-ILE, Homo sapiens]]
Article
9 sectionsContents
- Function
- Structure
- Regulation
- Evolution
- Role in disease
- Conformational changes
- Research
- See also
- References
thumb|dark green: Protein transport protein Sec23A, Homo sapiens, Gene names: SEC23Abrown: Protein transport protein Sec24A, Homo sapiens, Gene names: [[SEC24Ablue: Vesicle-trafficking protein SEC22b, Mus musculus, Gene names: SEC22B, Sec22l1pink: C-terminal sorting motif ILE-ILE, Homo sapiens]]
The coat protein complex II, or COPII, is a group of proteins that facilitate the formation of vesicles to transport proteins from the endoplasmic reticulum to the Golgi apparatus or endoplasmic-reticulum–Golgi intermediate compartment. This process is termed anterograde transport, in contrast to the retrograde transport associated with the COPI complex. COPII is assembled in two parts: first an inner layer of Sar1, Sec23, and Sec24 forms; then the inner coat is surrounded by an outer lattice of Sec13 and Sec31.