scrapie
Sign in to savethumb|Ewe with scrapie with weight loss and hunched appearance thumb|Same ewe as above with bare patches on rear end from scraping
Article
14 sectionsContents
- Regulation
- Cause
- Transmission and pathogenesis
- Clinical signs and diagnosis
- Treatment and preventive action
- Transmission/exposure pathways
- Exposure through contaminated vaccines
- Exposure through contaminated soil
- Exposure through contaminated hay mites
- Transmission summary
- Genetics
- See also
- References
- External links
thumb|Ewe with scrapie with weight loss and hunched appearance thumb|Same ewe as above with bare patches on rear end from scraping
Scrapie () is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be caused by a prion. Scrapie has been known since at least 1732 and does not appear to be transmissible to humans. However, it has been found to be experimentally transmissible to humanised transgenic mice and non-human primates.