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scrapie
EntityQ170102· pop 31· linked from 97 articles

thumb|Ewe with scrapie with weight loss and hunched appearance thumb|Same ewe as above with bare patches on rear end from scraping

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Scrapie
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~21 min read

Article

14 sections
Contents
  • Regulation
  • Cause
  • Transmission and pathogenesis
  • Clinical signs and diagnosis
  • Treatment and preventive action
  • Transmission/exposure pathways
  • Exposure through contaminated vaccines
  • Exposure through contaminated soil
  • Exposure through contaminated hay mites
  • Transmission summary
  • Genetics
  • See also
  • References
  • External links

thumb|Ewe with scrapie with weight loss and hunched appearance thumb|Same ewe as above with bare patches on rear end from scraping

Scrapie () is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be caused by a prion. Scrapie has been known since at least 1732 and does not appear to be transmissible to humans. However, it has been found to be experimentally transmissible to humanised transgenic mice and non-human primates.

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