SEMG2
Sign in to saveAlso known as SGII, semenogelin II, semenogelin 2
Semenogelin-2 is a protein that in humans is encoded by the SEMG2 gene.
Gene data
SEMG2- Name
- semenogelin 2
- Type
- protein-coding
- Position
- 45,221,373–45,224,462 (+)
- Aliases
- SGII
- Ensembl
- ENSG00000124157
- RefSeq RNA
- NM_003008.3
- RefSeq protein
- NP_002999.1
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
semenogelin 2
- Symbol
- SEMG2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:45,221,373-45,224,462
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- exact match
- identifiers.org/ncbigene/6407
- found in taxon
- Homo sapiens
- HomoloGene ID
- 129832
- chromosome
- human chromosome 20
- genomic end
- 43853099
- genomic start
- 45221373
- cytogenetic location
- 20q13.12
- expressed in
- muscular system
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Semenogelin-2 is a protein that in humans is encoded by the SEMG2 gene.
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.
Excerpted from Wikipedia’s “SEMG2” article, available under the CC BY-SA 4.0 licence.