semenogelin
Sign in to saveAlso known as IPR008836
Semenogelin is a protein that is involved in the formation of a gel matrix that encases ejaculated spermatozoa, preventing capacitation. It blocks capacitation mainly via inhibition of reactive oxygen species (ROS) generation.
Wikidata facts
- Instance of
- protein family
- Subclass of
- protein
Show 1 more fact
- produced by
- seminal vesicula
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Semenogelin is a protein that is involved in the formation of a gel matrix that encases ejaculated spermatozoa, preventing capacitation. It blocks capacitation mainly via inhibition of reactive oxygen species (ROS) generation.
Proteolysis by prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The cleavage products of the semenogelins constitute the main antibacterial components in human seminal plasma.
Excerpted from Wikipedia’s “semenogelin” article, available under the CC BY-SA 4.0 licence.