Also known as senolytic, Senotherapeutics
A senolytic (from the words senescence and -lytic, "decomposition or breakdown") is among a class of small molecules under basic research to determine if they can selectively induce death of senescent cells and improve health in humans. A goal of this research is to discover or develop agents to delay, prevent, alleviate, or reverse age-related diseases. Removal of senescent cells with senolytics has been proposed as a method of enhancing immunity during aging.
Research
2,641 papers- Cellular senescence and senolytics: the path to the clinic.Nature medicine · 2022
- Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.The FEBS journal · 2023
- The Role of Senolytics in Osteoporosis.Biomolecules · 2025
- Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging Interventions.Biomolecules · 2025
- The potential of Senolytics in transplantation.Mechanisms of ageing and development · 2021
via PubMed
Article · 中文
反老藥(Senolytic)是一類受到基礎科學研究以確定其是否能選擇性地殺死衰老細胞並增進人體健康的小分子物質;這類研究的目標是找出或開發能延緩、阻止、紓解甚至逆轉老化相關疾病的藥物。與此類研究相關的一個概念是「凍齡」(senostatic),其意為抑制老化。
Abstract from DBpedia / Wikipedia · CC BY-SA