Gene data
SIRT7- Name
- sirtuin 7
- Type
- protein-coding
- Position
- 81,911,939–81,921,323 (−)
- Aliases
- SIR2L7
- Ensembl
- ENSG00000187531
- RefSeq RNA
- NM_016538.3, XM_011523580.2, XM_047436228.1, XM_047436229.1, XM_047436230.1
- RefSeq protein
- NP_057622.1, XP_011521882.1, XP_047292184.1, XP_047292185.1, XP_047292186.1
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
chromatin bindingprotein bindingprotein methyltransferase activityNAD-dependent protein lysine deacetylase activityNAD-dependent protein lysine deacetylase activityNAD-dependent protein lysine deacetylase activityprotein-succinyllysine desuccinylase activityprotein-succinyllysine desuccinylase activity
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
sirtuin 7
- Symbol
- SIRT7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,911,939-81,921,323
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 56152
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51547
- genomic end
- 79879199
- genomic start
- 79869815
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.3
Sources (3)
via Wikidata · CC0