Structure via PubChem · Public domain (PubChem)
SM-102
Sign in to saveAlso known as heptadecan-9-yl 8-[2-hydroxyethyl-(6-oxo-6-undecoxyhexyl)amino]octanoate, heptadecan-9-yl-8-{(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino}octanoate
SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. These are used for the delivery of mRNA-based vaccines, and in particular SM-102 forms part of the drug delivery system for the Moderna COVID-19 vaccine.
Chemical data
- Formula
- C44H87NO5
- Molecular weight
- 710.2 g/mol
- IUPAC name
- heptadecan-9-yl 8-[2-hydroxyethyl-(6-oxo-6-undecoxyhexyl)amino]octanoate
- SMILES
- CCCCCCCCCCCOC(=O)CCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCO
- InChIKey
- BGNVBNJYBVCBJH-UHFFFAOYSA-N
- XLogP
- 15.5
- Polar surface area
- 76.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 709.6584248840002
Show 2 more facts
- canonical SMILES
- CCCCCCCCCCCOC(=O)CCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCO
- chemical formula
- C₄₄H₈₇NO₅
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
{{chembox | Name = SM-102 | ImageFile = SM-102 Structural formula V1.svg | ImageClass = skin-invert-image | PIN = 9-Heptadecanyl 8-{(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino}octanoate | OtherNames = 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate |Section1= |Section2= }}
SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. These are used for the delivery of mRNA-based vaccines, and in particular SM-102 forms part of the drug delivery system for the Moderna COVID-19 vaccine.
Excerpted from Wikipedia’s “SM-102” article, available under the CC BY-SA 4.0 licence.